New study: could a daily supplement and strength training beat menopause blues?

NCT ID NCT07135232

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a plant-based supplement (sarmentosin and L-theanine) combined with home strength training can improve mood, sleep, and muscle health in women going through perimenopause. 72 women aged 40-55 will be split into four groups: supplement plus exercise, supplement only, placebo plus exercise, or placebo only. They will take capsules daily and some will do resistance exercises three times a week for 12 weeks, with regular check-ups on symptoms and cognition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Sarmentosin and L-theanine supplement
What this could lead to
If it works, this could offer a non-hormonal option to help manage perimenopausal symptoms and maintain muscle strength.
What could go wrong
This is a small, early-stage trial with 72 participants, so results may not apply to everyone. The supplement is new and its long-term effects are unknown.

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Conditions

The condition(s) this trial relates to.

anxiety disorder Depression Hot Flashes Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Carnegie School of Sport

    RECRUITING

    Leeds, North Humberside, LS2 3AE, United Kingdom

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