Stress relief: could a simple hormone boost ease fatigue in PMR/GCA patients?

NCT ID NCT05435781

Recruiting now Symptom relief Sponsor: Marianne Christina Klose Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether taking extra hydrocortisone during times of mild to moderate stress (physical or mental) can improve health-related quality of life, especially fatigue, in people with polymyalgia rheumatica (PMR) or giant cell arteritis (GCA) who are on long-term, low-dose prednisolone. Participants will be randomly assigned to receive either hydrocortisone or a placebo during stressful periods and will report their symptoms via a smartphone app. The goal is to see if this approach helps manage fatigue and other stress-related symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ADRENAL INSUFFICIENCY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

adrenocortical insufficiency Giant Cell Arteritis polymyalgia rheumatica secondary adrenal insufficiency temporal arteritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADRENAL INSUFFICIENCY GIANT CELL ARTERITIS POLYMYALGIA RHEUMATICA

Contacts and locations

Locations

Department of Endocrinology, Aarhus University Hospital
RECRUITING

Aarhus, Denmark
Department of Endocrinology, Odense University Hospital
RECRUITING

Odense, Denmark
Department of Medical Endocrinology, Copenhagen University Hospital, Rigshospitalet
RECRUITING

Copenhagen, 2100, Denmark

More trials for these conditions

Other studies related to the condition(s) this trial covers.