Could a Once-Daily steroid pill improve blood sugar control in Dual-Disease patients?
NCT ID NCT05716607
First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time
Summary
This trial tests whether taking hydrocortisone once a day (as a dual-release pill) leads to more stable blood sugar levels compared to the standard three-times-a-day regimen in adults who have both insulin-treated diabetes and Addison's disease. Participants will try both schedules in a random order, and researchers will track glucose patterns, HbA1c, and cortisol levels. The goal is to find a dosing strategy that simplifies treatment while improving glycemic control.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Once-daily dual-release hydrocortisone vs thrice-daily immediate-release hydrocortisone
- What this could lead to
- If it works, this could point toward a simpler, more effective hydrocortisone dosing schedule for people with both diabetes and Addison's disease, potentially improving blood sugar control.
- What could go wrong
- This is a small, early-stage crossover trial, so results may not apply to everyone. The benefit of once-daily dosing may be modest or absent, and individual responses can vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
Sahlgrenska University Hospital
Gothenburg, Sweden
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