Secondary adrenal insufficiency
MONDO:0043370A hormonal disorder that occurs when lack of corticotropin-releasing hormone (CRH) secretion from the hypothalamus or adrenocorticotropic hormone (ACTH) secretion from the pituitary is responsible for hypofunction of the adrenal cortex.
Also known as: central Hypoadrenalism, central adrenal insufficiency, hypocortisolism secondary to another disorder, secondary adrenal insufficiency, secondary adrenocortical insufficiency, secondary hypocortisolism
5 clinical trials for this condition and its sub-types.
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Steroid tapering showdown: quick stop vs. slow wean in inflammation patients
Disease control Recruiting nowThis study looks at whether people with inflammatory or autoimmune diseases can safely stop taking steroids (like prednisone) right away instead of slowly reducing the dose over 4 weeks. The goal is to see if stopping quickly leads to more hospital visits or adrenal crises. About…
Phase: PHASE4 • Sponsor: University Hospital, Basel, Switzerland • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Stress relief: could a simple hormone boost ease fatigue in PMR/GCA patients?
Symptom relief Recruiting nowThis study looks at whether taking extra hydrocortisone during times of mild to moderate stress (physical or mental) can improve health-related quality of life, especially fatigue, in people with polymyalgia rheumatica (PMR) or giant cell arteritis (GCA) who are on long-term, low…
Phase: PHASE4 • Sponsor: Marianne Christina Klose • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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New imaging tracer could shed light on adrenal cholesterol
Knowledge-focused Recruiting nowThis study tests a special radioactive tracer called [18F]FNP-59 to see if it can safely and clearly show cholesterol activity in the adrenal gland using PET scans. About 24 people will take part, including healthy volunteers and those with known adrenal problems. The goal is to …
Phase: EARLY_PHASE1 • Sponsor: Benjamin Viglianti • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC