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Steroid tapering showdown: quick stop vs. slow wean in inflammation patients

NCT ID NCT03153527

Recruiting now Disease control Sponsor: University Hospital, Basel, Switzerland Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether people with inflammatory or autoimmune diseases can safely stop taking steroids (like prednisone) right away instead of slowly reducing the dose over 4 weeks. The goal is to see if stopping quickly leads to more hospital visits or adrenal crises. About 530 adults who have been on steroids for at least a month will participate.

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Conditions

The condition(s) this trial relates to.

adrenocortical insufficiency autoimmune disease inflammatory disease secondary adrenal insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTOIMMUNE INFLAMMATORY DISORDER

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Center for Primary Health Care,University of Basel, Kantonsspital Baselland

    TERMINATED

    Liestal, 4410, Switzerland

  • Departement of Internal Medicine, Kantonsspital Aarau

    RECRUITING

    Aarau, 5001, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of Internal Medicine, Kantonsspital Münsterlingen

    RECRUITING

    Münsterlingen, 8596, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Department of Internal Medicine, Kantonsspital St. Gallen

    RECRUITING

    Sankt Gallen, 9007, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of Rheumatology, Immunology, and Allergology, Inselspital

    TERMINATED

    Bern, 3010, Switzerland

  • Dept. of Endocrinology, Diabetology and Clinical Nutrition, University Hospital

    TERMINATED

    Zurich, 8091, Switzerland

  • Division of Gastroenterology, Spital Bülach AG

    TERMINATED

    Bülach, 8180, Switzerland

  • Endocrinology/Diabetology/Metabolism; University Hospital Basel

    TERMINATED

    Basel, 4031, Switzerland

  • Geneva University Hospitals

    RECRUITING

    Geneva, 1205, Switzerland

    Contact Phone: •••-•••-••••

    Contact

  • Internal Medicine, Kantonsspital Baselland/Liestal

    RECRUITING

    Liestal, 4410, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kantonsspital Baden

    RECRUITING

    Baden, 5404, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kantonsspital Frauenfeld

    RECRUITING

    Frauenfeld, 8501, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • St. Claraspital Basel

    RECRUITING

    Basel, 4058, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Stoffwechselzentrum, Kantonsspital Olten

    TERMINATED

    Olten, 4600, Switzerland

  • University Hospital Frankfurt

    RECRUITING

    Frankfurt, Germany

    Contact

    Contact

    Contact

  • University Hospital Würzburg

    RECRUITING

    Würzburg, 97080, Germany

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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