Heartburn drug may shield seniors from bleeding while on blood thinners

NCT ID NCT06393868

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests whether omeprazole, a common heartburn drug, can reduce gastrointestinal bleeding in adults 65 and older who take blood thinners for blood clots. Researchers will enroll 360 participants to see if a larger trial is feasible. The study focuses on recruitment and adherence, not yet on proving the drug works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Omeprazole (a proton pump inhibitor)

What this could lead to

If this pilot succeeds, it could lead to a larger study that may show omeprazole helps prevent stomach bleeding in older adults taking blood thinners for blood clots.

What could go wrong

This is a small pilot study to test feasibility, not effectiveness. It may not prove omeprazole works, and results may not apply to all patients. Omeprazole can have side effects like headache or diarrhea.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Gastrointestinal Hemorrhage thrombotic disease venous thromboembolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Québec-Université Laval; Hôpital Saint-François d'Assise

    RECRUITING

    Québec, Quebec, G1R2J6, Canada

    Contact

    Contact Email: •••••@•••••

  • CIUSSS de l'Est-de- l'Île-de-Montréal

    NOT_YET_RECRUITING

    Montreal, Quebec, H1T2M4, Canada

    Contact Email: •••••@•••••

    Contact

  • Centre hospitalier de l'Université de Montréal

    RECRUITING

    Montreal, Quebec, H2X 0A9, Canada

    Contact Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

  • Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval

    RECRUITING

    Québec, Quebec, G1V4G5, Canada

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • Niagara Health System - St. Catharines Site

    NOT_YET_RECRUITING

    St. Catharines, Ontario, L2S 0A9, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Ottawa Hospital

    RECRUITING

    Ottawa, Ontario, K1H 8L6, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • University Health Network - Toronto General

    RECRUITING

    Toronto, Ontario, M5G 2c4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact