Could a blood draw help men with no sperm become fathers?

NCT ID NCT05479474

Recruiting now Disease control Sponsor: Stanford University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Stanford study tests whether injecting a man's own platelet-rich plasma (PRP) into his testicles can help produce sperm. Ten men with nonobstructive azoospermia who previously failed sperm retrieval will receive the injection. Three months later, doctors will check for sperm and, if found, use it for IVF.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: platelet-rich plasma (PRP)
What this could lead to: If it works, this could offer a new option for men with no sperm in their ejaculate to father biological children using their own sperm.
What could go wrong: This is a very early, tiny trial with only 10 participants. The procedure is experimental, may not produce sperm, and carries risks from the injection and blood draw.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AZOOSPERMIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

azoospermia male infertility spermatogenic failure 3 spermatogenic failure, Y-linked, 2

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AZOOSPERMIA MALE INFERTILITY NONOBSTRUCTIVE AZOOSPERMIA

Contacts and locations

Locations

Stanford Urology Clinic
RECRUITING

Stanford, California, 94304, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.