Could a blood draw help men with no sperm become fathers?

NCT ID NCT05479474

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Stanford study tests whether injecting a man's own platelet-rich plasma (PRP) into his testicles can help produce sperm. Ten men with nonobstructive azoospermia who previously failed sperm retrieval will receive the injection. Three months later, doctors will check for sperm and, if found, use it for IVF.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

platelet-rich plasma (PRP)

What this could lead to

If it works, this could offer a new option for men with no sperm in their ejaculate to father biological children using their own sperm.

What could go wrong

This is a very early, tiny trial with only 10 participants. The procedure is experimental, may not produce sperm, and carries risks from the injection and blood draw.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

azoospermia male infertility spermatogenic failure 3 spermatogenic failure, Y-linked, 2

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Stanford Urology Clinic

    RECRUITING

    Stanford, California, 94304, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••