Probiotics vs. Weight-Loss drug: which helps you shed pounds?
NCT ID NCT06989177
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a probiotic (Lactobacillus paracasei) or the drug semaglutide can help overweight or obese adults lose weight and improve metabolism. Over 12 weeks, 140 participants will follow a reduced-calorie diet and lifestyle program while taking one of these or a placebo. The goal is to see which approach works best for weight loss and long-term health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Lactobacillus paracasei LC-19 (a probiotic) and semaglutide (a weight-loss drug)
What this could lead to
If successful, this could show that a specific probiotic helps with weight loss and metabolic health, offering a natural alternative or complement to drugs like semaglutide.
What could go wrong
This is a small, early-stage trial (140 people) with no phase designation. Results may not apply to everyone, and probiotics often have modest effects. Side effects or lack of long-term benefit are possible.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for OBESITY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences
RECRUITINGHangzhou, Zhejiang, 310024, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact