New approach: chemo before radiation may improve brain tumor treatment

NCT ID NCT07439172

First seen Mar 22, 2026 · Last updated Jun 12, 2026 · Updated 12 times

Summary

This study tests giving chemotherapy before radiation for people with high-grade gliomas, an aggressive brain cancer. The goal is to see if this order makes it easier to read MRI scans and find effective drugs faster. About 70 adults aged 18-80 with measurable tumor after surgery will receive temozolomide first, then standard radiation. This is a phase 2 trial to check response and safety.

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