Blood filter could curb septic shock deaths

NCT ID NCT03901807

First seen Jan 11, 2026 · Last updated May 17, 2026 · Updated 24 times

Summary

This study tests whether adding a special blood-filtering cartridge (PMX) to usual hospital care can help people with septic shock caused by endotoxins. About 150 adults with severe low blood pressure needing strong medicines will be randomly assigned to get the filter plus standard care or standard care alone. The main goal is to see if the filter lowers the number of deaths within 28 days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Baystate Medical Center

    Springfield, Massachusetts, 01199, United States

  • CHI Memorial

    Chattanooga, Tennessee, 37404, United States

  • Cooper Health System

    Camden, New Jersey, 08103, United States

  • Emory University

    Atlanta, Georgia, 30322, United States

  • George Washington University

    Washington D.C., District of Columbia, 20037, United States

  • Institute for Extracorporeal Life Support

    San Antonio, Texas, 78229, United States

  • Louisiana State University Health Shreveport

    Shreveport, Louisiana, 71103, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Mt Sinai Hospital

    New York, New York, 10029, United States

  • Parkridge Hospital

    Chattanooga, Tennessee, 37404, United States

  • Pulmonary Associates

    Boulder, Colorado, 80909, United States

  • Rutgers, The State University of New Jersey

    Piscataway, New Jersey, 08854, United States

  • Stony Brook University

    Stony Brook, New York, 11794, United States

  • The University of Texas Health Science Center at Houston

    Houston, Texas, 77030, United States

  • UPMC

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294-0111, United States

  • University of Arkansas for Medical Sciences

    Little Rock, Arkansas, 72205, United States

  • University of California, San Francisco

    San Francisco, California, 94143, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

Conditions

Explore the condition pages connected to this study.