Heart surgery upgrade: zap away bad rhythms while implanting pump

NCT ID NCT05034432

Recruiting now Disease control Sponsor: University of Rochester Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 15, 2026 · Updated 2 times

Summary

This study tests whether destroying small areas of heart muscle that cause dangerous rhythms (ventricular tachycardia ablation) during LVAD implant surgery can reduce the number of these rhythms after surgery. About 100 adults with advanced heart failure who are getting an LVAD will be randomly assigned to either receive the ablation during surgery or standard care. The main goal is to see if the ablation lowers the total number of dangerous heart rhythm events.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Intra-operative ventricular tachycardia ablation (a procedure to destroy small areas of heart muscle that cause abnormal rhythms)
What this could lead to: If it works, this could reduce dangerous heart rhythms after LVAD surgery, potentially lowering hospitalizations and improving recovery.
What could go wrong: This is a phase 4 trial with only 100 participants, so results may not apply to everyone. The ablation itself carries risks like bleeding or damage to the heart.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Arrhythmias, Cardiac cardiac rhythm disease cardiomyopathy ventricular fibrillation ventricular tachycardia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARRYTHMIA CARDIOMYOPATHIES

Contacts and locations

Locations

Ascension St. Vincent Indianapolis
RECRUITING

Indianapolis, Indiana, 46260, United States
Banner University Medical Center
RECRUITING

Phoenix, Arizona, 85006, United States
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States
Columbia University Medical Center
RECRUITING

New York, New York, 10026, United States
Emory University
RECRUITING

Atlanta, Georgia, 30322, United States
Henry Ford Health
RECRUITING

Detroit, Michigan, 48202, United States
Houston Methodist Hospital
RECRUITING

Houston, Texas, 77030, United States
Johns Hopkins University
RECRUITING

Baltimore, Maryland, 21287, United States
Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States
Medstar Washington Hospital Center
RECRUITING

Washington D.C., District of Columbia, 20010, United States
Piedmont Heart Institute
RECRUITING

Atlanta, Georgia, 30309, United States
Tufts Medical Center
RECRUITING

Boston, Massachusetts, 02111, United States
UCLA Cardiac Arrthmia Center
RECRUITING

Los Angeles, California, 90095, United States
UPMC
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
Univedrsity of Louisville
RECRUITING

Louisville, Kentucky, 40202, United States
University of California San Francisco
RECRUITING

San Francisco, California, 94143, United States
University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
University of Rochester
RECRUITING

Rochester, New York, 14642, United States
Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37232, United States

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