New PET tracer aims to detect hidden implant infections
NCT ID NCT05889286
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new radioactive tracer called [F-18]MHF to see if it can detect infections around knee implants using PET scans. Researchers will compare the tracer's uptake in infected versus non-infected implants in 18 adults. The goal is to improve diagnosis and reduce unnecessary surgeries for suspected infections.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Fluorine-18 Maltodextrin ([F-18]MHF)
- What this could lead to
- If successful, this could provide a more accurate way to diagnose infections around implants, helping doctors decide if surgery is needed.
- What could go wrong
- This is a small, early-phase study with only 18 participants. The tracer may not reliably distinguish infected from non-infected implants in larger groups.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Emory University Hospital
Atlanta, Georgia, 30322, United States
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