Knee infection breakthrough? one surgery may replace two
NCT ID NCT06293352
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a single surgery to replace an infected artificial knee works as well as the standard two-surgery approach. About 153 patients with a chronic knee infection will be randomly assigned to one of the two treatments. Researchers will track pain, function, and satisfaction for 5 years to see which method patients prefer and which provides better long-term results.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- antibiotic cement spacer
- What this could lead to
- If successful, this study could show that a single surgery works as well as two surgeries for treating knee infections, saving patients time and improving knee function sooner.
- What could go wrong
- This is a mid-stage study with 153 participants, so results may not apply to everyone. The one-stage spacer may need replacement sooner than a standard artificial knee.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Northwestern Medicine
RECRUITINGChicago, Illinois, 60611, United States
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