Could a drug combo boost Post-Surgery recovery?
NCT ID NCT07308756
First seen Jan 04, 2026 · Last updated Jun 23, 2026 · Updated 28 times
Summary
This study tests whether giving dexmedetomidine and esketamine during and after surgery can help patients recover better. 316 adults having general anesthesia will receive one or both drugs, and their recovery quality will be measured using a 15-item questionnaire. The goal is to see if these drugs improve pain control, sleep, and overall well-being after surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Peking University First Hospital
RECRUITINGBeijing, Beijing Municipality, 100034, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dexmedetomidine and esketamine
What this could lead to
If successful, this could point toward a simple way to improve pain control and sleep quality after surgery, helping patients recover faster and feel better.
What could go wrong
This is a Phase 4 trial, but it is still relatively small (316 people) and tests two drugs already in use. The benefits may be modest, and individual results can vary. Side effects like slow heart rate or nausea are possible.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.