Can a 15-Day course of paxlovid ease long COVID?
NCT ID NCT05576662
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether taking Paxlovid for 15 days can reduce severe Long COVID symptoms like fatigue, brain fog, and shortness of breath. 168 adults with persistent symptoms after COVID-19 took either the drug or a placebo. Researchers tracked symptom severity over 15 weeks to see if the treatment helped.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Paxlovid (nirmatrelvir and ritonavir)
- What this could lead to
- If it works, this could point toward a treatment for Long COVID symptoms.
- What could go wrong
- This is a small, early-phase pilot trial, so results may not apply to everyone. The drug may not significantly reduce symptoms, and side effects are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
Stanford University
Stanford, California, 94305, United States
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