Obesity may affect immune drug dosing – study seeks answers
NCT ID NCT04818177
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study investigates how obesity affects the way the body processes intravenous immune globulin (IVIG), a treatment for immune deficiencies. Researchers measured body composition and blood levels of IVIG in 40 obese and normal-weight patients to find the best dosing strategy. The goal is to reduce side effects from overdosing and ensure effective treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- intravenous immune globulin (IVIG)
- What this could lead to
- If successful, this study could lead to better dosing guidelines for IVIG in obese patients, reducing side effects and improving treatment outcomes.
- What could go wrong
- This is a small, observational study with only 40 participants, so results may not apply to all patients. It does not test a new treatment, only refines existing dosing.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Robert Wood Johnson University Hospital Somerset
Somerville, New Jersey, 08876, United States
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