Personalized weight loss? study links genes, gut bugs to tirzepatide success

NCT ID NCT07650149

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how a person's genetics, gut microbiome, and behaviors influence how well they tolerate and respond to the weight-loss drug tirzepatide. Researchers will follow 200 overweight or obese adults for up to 12 months, tracking weight changes, side effects, and whether they stay on the medication. The goal is to find clues that could help tailor obesity treatment to each individual.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tirzepatide

What this could lead to

If successful, this could help doctors personalize obesity treatment by predicting who will benefit most from tirzepatide based on their genes and gut bacteria.

What could go wrong

This is an observational study, not a treatment trial. It won't prove that tirzepatide works, only that certain factors may influence its effects. Results may not apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight Patient Compliance

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Luxmed sp zoo

    RECRUITING

    Warsaw, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Waga Zmiany

    RECRUITING

    Krakow, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••