Simpler Weight-Loss surgery put to the test against gold standard
NCT ID NCT06057597
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two types of gastric bypass surgery for people with severe obesity: the standard Roux-en-Y and a simpler omega (one-anastomosis) bypass with a shorter intestinal loop. Researchers want to see if the omega procedure is just as good at helping patients lose weight and has a similar rate of nutritional problems. About 368 adults will be followed for two years after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Gastric bypass surgery (omega or Roux-en-Y)
- What this could lead to
- If successful, this could offer a simpler, equally effective surgical option for weight loss with fewer complications.
- What could go wrong
- This is a non-inferiority trial, so it may only show the omega bypass is not worse, not better. Results are at 2 years, and long-term effects are unknown.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hôpital Bichat Claude-Bernard
RECRUITINGParis, France
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