Scientists investigate the mystery of weight regain
NCT ID NCT05748158
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at why people with obesity often regain weight after losing it through a behavioral weight loss program. About 205 adults aged 25-59 will first lose at least 7% of their body weight, then be followed for a year to track how much weight they regain. The goal is to understand the body's physiological changes that make weight maintenance difficult.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could reveal why some people regain weight after dieting, pointing toward better strategies to maintain weight loss.
What could go wrong
This is an observational study, not a treatment trial. It may not lead to any direct intervention, and results may not apply to everyone with obesity.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Columbia University Irving Medical Center
RECRUITINGNew York, New York, 10032, United States
Contact Email: •••••@•••••
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Contact
Contact Email: •••••@•••••
Contact
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Drexel University
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Email: •••••@•••••
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Email: •••••@•••••
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Contact Email: •••••@•••••
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