Tiny study probes why stomach balloons and stapling help people lose weight
NCT ID NCT04306445
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study looked at how gas-filled stomach balloons and a procedure called endoscopic sleeve gastroplasty affect stomach emptying, hunger hormones, and appetite in people with obesity. Researchers compared these treatments to a meal replacement program. The goal was to understand the mechanisms behind weight loss, not to test a new treatment. Only 3 people were enrolled before the study was stopped.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Obalon Balloon (gas-filled intragastric balloon) and endoscopic sleeve gastroplasty
What this could lead to
If successful, this could help doctors understand why these weight loss procedures work, potentially leading to better patient selection and longer-lasting results.
What could go wrong
This was a very small pilot study (only 3 participants) that was terminated early, so results are limited and may not apply to the general population.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Colorado
Aurora, Colorado, 80045, United States