Diet and exercise may fight frailty in prostate cancer survivors

NCT ID NCT03880422

Recruiting now Symptom relief Sponsor: Roswell Park Cancer Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether personalized nutrition and exercise plans can reduce frailty and improve body composition in prostate cancer survivors who are on hormone therapy (ADT). Fifty participants will receive diet advice, exercise coaching, and educational sessions. Researchers will measure changes in muscle mass, fat, strength, and mobility over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dietary plan, exercise program, and educational sessions
What this could lead to: If successful, this could show that personalized nutrition and exercise help prostate cancer patients feel stronger, reduce frailty, and improve body composition during hormone therapy.
What could go wrong: This is a small early-phase study (50 people) with no control group, so results may not apply broadly. Benefits may be modest or not sustained.

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Conditions

The condition(s) this trial relates to.

metastatic prostate carcinoma Obesity obesity disorder Overweight prostate adenocarcinoma prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER SURVIVOR OBESITY OVERWEIGHT PROSTATE ADENOCARCINOMA STAGE A PROSTATE CANCER STAGE B PROSTATE CANCER STAGE C PROSTATE CANCER STAGE D PROSTATE CANCER STAGE I PROSTATE CANCER STAGE II PROSTATE CANCER STAGE IIA PROSTATE CANCER STAGE IIB PROSTATE CANCER STAGE IIC PROSTATE CANCER STAGE III PROSTATE CANCER STAGE IIIA PROSTATE CANCER STAGE IIIB PROSTATE CANCER STAGE IIIC PROSTATE CANCER STAGE IV PROSTATE CANCER STAGE IVA PROSTATE CANCER STAGE IVB PROSTATE CANCER

Contacts and locations

Locations

Roswell Park Cancer Institute
RECRUITING

Buffalo, New York, 14263, United States

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