Sound waves aimed at the brain: a new way to treat movement disorders?
NCT ID NCT06232629
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study explores whether low-intensity ultrasound can safely and precisely stimulate deep brain regions in people with Parkinson's disease or dystonia. Ten participants who already have deep brain stimulation (DBS) implants will receive ultrasound pulses while researchers record brain activity from the implants. The goal is to understand how ultrasound affects brain signals, not to treat symptoms directly.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- low-intensity transcranial ultrasound stimulation (TUS) via NeuroFUS device
- What this could lead to
- If successful, this could point toward a noninvasive way to adjust brain activity in movement disorders, potentially reducing the need for invasive surgery.
- What could go wrong
- This is a very early, small study (10 people) focused on safety and brain signals, not treatment effects. It may not lead to any clinical benefit, and ultrasound effects on deep brain areas are still uncertain.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
Toronto Western Hospital
Toronto, Ontario, M5T 2S8, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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