Wearable sensors aim to catch neurodegenerative decline in real time

NCT ID NCT04753320

First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This observational study tests whether wearable sensors and digital health tools can reliably measure falls, movement, speech, and thinking skills in people with progressive supranuclear palsy, Parkinson's disease, or multiple system atrophy. Participants wear a pendant sensor and complete monthly remote assessments plus in-person visits every six months for about a year. The goal is to see if this approach is practical and accurate enough for home monitoring.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this approach could enable more frequent, real-world tracking of disease progression in neurodegenerative conditions, potentially improving clinical trial efficiency and patient care.
What could go wrong
This is an early feasibility study with only 85 participants. The technology may not be accurate enough or acceptable to patients over the long term.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins

    Baltimore, Maryland, 21093, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

    Contact Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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