Knee pain relief: synthetic fluid injection shows promise in Long-Term study
NCT ID NCT06523491
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study followed 57 people with knee osteoarthritis for one year after they received an injection of NOLTREX™, a synthetic joint fluid. Researchers measured changes in pain, stiffness, and physical function using a standard questionnaire. The goal was to see if the injection provides lasting relief and is safe over the long term.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
NOLTREX™ (a synthetic joint fluid injection)
What this could lead to
If successful, this could provide a long-lasting option to ease pain and improve knee function in people with moderate knee osteoarthritis.
What could go wrong
This is a small, completed study with only 57 participants. The results are based on survey data, not a new treatment trial, so benefits may not be as strong in larger, more diverse groups.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Private Healthcare Facilty "Clinical hospital "RZHD-Medicina" of the city Saint-Petersburg
Saint Petersburg, Russia
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State budgetary healthcare facility of Yaroslavl Region "Clinical hospital №3"
Yaroslavl, Russia