Can a mask prevent breathing failure in obese ICU patients?
NCT ID NCT04014920
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether using a non-invasive ventilation (NIV) mask right after removing a breathing tube can prevent respiratory failure in obese intensive care patients. About 1000 obese adults were randomly assigned to receive either NIV or oxygen therapy. The goal was to see which approach reduces the need for re-intubation or other breathing support failures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
non-invasive ventilation (NIV) and oxygen therapy (high-flow nasal oxygen or standard oxygen)
What this could lead to
If NIV proves superior, it could become the standard post-extubation care for obese ICU patients, reducing the need for re-intubation.
What could go wrong
This is a completed trial, but results may not apply to all obese patients or settings. NIV can cause discomfort or skin damage, and some patients may still need re-intubation.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Centre Hospitalier Universitaire Saint Eloi
Montpellier, Herault, 34000, France