New CPR technique could save more newborn lives
NCT ID NCT06577818
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two CPR methods for newborns with cardiac arrest: a new technique that combines chest compressions with sustained lung inflation versus the standard 3:1 compression-to-ventilation ratio. Researchers will enroll 554 newborns across multiple hospitals to see which method reduces death before leaving the hospital. The goal is to find the safest and most effective way to restart the heart and breathing.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Chest compression during sustained inflation (CC+SI) procedure
- What this could lead to
- If this works, it could offer a better way to perform CPR on newborns, potentially saving more lives during resuscitation.
- What could go wrong
- This is an early-stage trial with 554 participants, and the new method may not prove better than the current standard. There are also risks of lung injury from sustained inflation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Royal Alexandra Hospital
Edmonton, Canada
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