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Balloon in the aorta could boost CPR success in cardiac arrest

NCT ID NCT04596514

Ongoing Disease control Sponsor: St. Olavs Hospital Source: ClinicalTrials.gov ↗

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This trial tests whether placing a balloon in the aorta (REBOA) during CPR can improve blood flow to the heart and brain in people who have a cardiac arrest outside the hospital. The study includes 200 adults with non-traumatic cardiac arrest who receive CPR within 10 minutes. Researchers compare standard CPR to CPR plus REBOA to see if the balloon helps restore a stable heartbeat and improves survival with good brain function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a balloon device called REBOA (resuscitative endovascular balloon occlusion of the aorta) placed inside the aorta during CPR
What this could lead to
If it works, this could provide a new way to improve blood flow to the heart and brain during CPR, potentially increasing survival after cardiac arrest.
What could go wrong
This is the first prospective trial of its kind, so results are uncertain. The procedure is invasive and may not improve outcomes or could cause complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiac arrest

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC ARREST

Contacts and locations

Locations

  • Aarhus Base

    Aarhus, Denmark

  • Billund HEMS-base

    Billund, Denmark

  • Drammen Hospital

    Drammen, Norway

  • Haukeland University Hospital

    Bergen, Norway

  • Lørenskog HEMS Unit

    Oslo, Norway

  • Maggiore Hospital

    Bologna, Italy

  • Rapid response car - 119 Oslo

    Oslo, Norway

  • Ringsted HEMS-base

    Ringsted, Denmark

  • Skive HEMS

    Skive, Denmark

  • St Olavs Hospital

    Trondheim, 7030, Norway

  • Stavanger University Hospital

    Stavanger, 4068, Norway

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