New MRI technique could catch osteoarthritis years earlier

NCT ID NCT04536103

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aims to develop a faster and more consistent MRI method to detect early signs of osteoarthritis and other joint problems. Researchers will scan 88 healthy volunteers and patients with ACL tears using MRI machines from different manufacturers. The goal is to create a standardized tool that can reliably measure cartilage health, which could lead to earlier diagnosis and better monitoring of joint diseases.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
MRI scan
What this could lead to
If successful, this could provide a reliable, early way to diagnose osteoarthritis before it causes permanent damage, improving treatment timing.
What could go wrong
This is an early observational study focused on developing the imaging method, not testing a treatment. The new MRI technique may not prove accurate enough for widespread use.

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Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries arthropathy Bone Diseases, Infectious musculoskeletal system disorder osteoarthritis osteomyelitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cleveland Clinic Foundation

    RECRUITING

    Cleveland, Ohio, 44195, United States

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