MUSCULOSKELETAL DISEASES

This program provides access to an experimental drug, AOC 1044, for people with Duchenne muscular dystrophy (DMD) whose genetic mutation can be treated by skipping exon 44. The goal is to help control the disease by allowing the body to produce a shorter but still functional dyst…

This study compares two surgical techniques for treating wrist arthritis caused by old injuries. 170 adults with specific types of wrist collapse will be randomly assigned to have either a four-corner fusion or a three-corner fusion (which removes one small bone). The goal is to …

This study aims to develop faster and more reliable MRI scans to detect early signs of osteoarthritis and other joint diseases before they show up on X-rays. Researchers will test these new methods on 88 healthy volunteers and patients with ACL tears or early cartilage problems a…

This study compares two treatments for carpal tunnel syndrome: an ultrasound-guided injection and a small-incision surgery. Researchers will measure pain and hand function in 60 adults over 12 weeks. The goal is to find which approach provides better symptom relief.

This study is testing whether tiny, dissolvable beads called SakuraBead are safe and effective for reducing heel pain caused by plantar fasciitis. It will compare the beads to standard shockwave therapy in about 45 adults. The goal is to see if this new procedure provides better …

This study aims to create a secure national database by collecting routine health information from about 22,000 adults with muscle or joint problems seen in community or primary care clinics. Researchers will use this data to develop dashboards and reports that help clinics track…

This study looks at how changing the heel height and stiffness of an ankle-foot brace (AFO) affects walking in people who use one daily. About 40 adults with leg injuries or nerve problems will walk with different heel cushions while researchers measure motion, comfort, and pain.…

This study is translating the Generic Functional Index, a questionnaire that measures how well people can do daily activities, into Turkish. Researchers will test the new version on 200 adults with musculoskeletal disorders (like arthritis or back pain) to make sure it is accurat…

This study looks at how common muscle and bone pain is among dentists and dental students, and how much they know about proper work posture. About 90 people aged 25-60 who are either training to be a specialist or already are one will answer a questionnaire. The goal is to find w…

This study looks at how carpal tunnel syndrome (CTS) severity relates to sleep quality. Researchers will use ultrasound to examine the wrist and compare findings between 120 CTS patients and healthy volunteers. The goal is to better understand the link between nerve compression a…

This study follows 10,000 adults aged 18 and older for life to see if simple health measurements can predict how long and how well people age. Researchers will track deaths, diseases, and disabilities to find early warning signs. No treatments or drugs are tested—just observation…

This study is a survey for adults with rheumatic or musculoskeletal diseases living in Europe. Participants fill out online questionnaires about their healthcare, work, and social life. The goal is to gather information that helps researchers and doctors better understand the bur…