MUSCULOSKELETAL DISEASES

This study is comparing two different surgical techniques for wrist arthritis caused by an old injury. It will involve 170 adults who need surgery to fuse some of their wrist bones. Researchers will measure grip strength, pain, and movement over a year to see if removing one smal…

This study aims to see if a precise, ultrasound-guided injection can work as well as minor surgery for treating carpal tunnel syndrome. It will involve 60 people with the condition, who will be randomly assigned to receive either the injection or the surgical procedure. Researche…

This program provides access to an investigational drug called AOC 1044 for eligible patients with Duchenne muscular dystrophy (DMD) who have a specific genetic mutation (amenable to exon 44 skipping). It is for patients aged 6 and older who are living in the US, including those …

This study aims to develop faster, more reliable MRI scans to detect early cartilage damage and arthritis. Researchers will test these new scanning methods on healthy volunteers and people who recently tore their ACL, a group at high risk for developing arthritis. The goal is to …

This study is testing whether SakuraBead microspheres can safely reduce pain from plantar fasciitis (heel pain). Researchers will compare the microsphere treatment against standard shockwave therapy in 45 adults with diagnosed plantar fasciitis. Participants will be followed for …

This study is testing whether a new procedure using tiny, dissolvable beads injected into knee arteries works better than standard steroid injections for reducing arthritis pain. About 89 adults with moderate to severe knee osteoarthritis pain that hasn't improved with other trea…

This study aims to understand how office setup, posture, and work hours relate to neck, shoulder, and back pain among medical secretaries. Researchers will survey 110 hospital secretaries about their workstations, daily routines, and pain levels. The goal is to identify risk fact…

This study aims to understand how the severity of carpal tunnel syndrome (CTS) affects a person's sleep quality. Researchers will compare 120 patients with CTS to healthy people, using ultrasound scans to measure nerve swelling and questionnaires to assess pain and sleep patterns…

This is a survey study aiming to understand how rheumatic and musculoskeletal diseases (RMDs) affect people's daily lives, work, and healthcare. It will enroll 1,000 adults across Europe who have been diagnosed with an RMD. Participants will complete online questionnaires about t…

This study aims to create and test a Turkish version of a questionnaire that measures how muscle and bone problems affect a person's daily life. Researchers will give the questionnaire to 200 Turkish-speaking adults with musculoskeletal conditions to see if it is consistent and m…

This study aims to create a national tracking system to measure the quality of care for common muscle, bone, and joint problems like back pain and arthritis. It will involve up to 22,000 adult patients across community clinics and primary care services in the UK. The goal is to c…

This study aims to find the best heel cushion setup for ankle-foot braces (AFOs) to improve daily walking. Researchers will have 40 people who use AFOs walk with different heel cushions while measuring their movement, comfort, and pain. The goal is to gather evidence to help doct…