MUSCULOSKELETAL DISEASES
Clinical trials for MUSCULOSKELETAL DISEASES explained in plain language.
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Extended trial tests promising drug for genetic muscle disease
Disease control CompletedThis study continued testing an experimental drug called AOC 1001 in adults with myotonic dystrophy type 1, a genetic muscle-wasting disease. It followed 37 participants from a previous trial to check long-term safety and see if the drug continues to work when given every 8 weeks…
Matched conditions: MUSCULOSKELETAL DISEASES
Phase: PHASE2 • Sponsor: Avidity Biosciences, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New drug tested to ease debilitating knee arthritis pain
Symptom relief CompletedThis study tested whether an investigational drug called LEVI-04 could safely reduce pain and improve physical function in people with knee osteoarthritis. Over 500 participants with moderate to severe knee pain received either the drug or a placebo injection. The main goal was t…
Matched conditions: MUSCULOSKELETAL DISEASES
Phase: PHASE2 • Sponsor: Levicept • Aim: Symptom relief
Last updated Apr 01, 2026 14:43 UTC
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High-Tech navigation aims for better knee replacements
Symptom relief CompletedThis study tested a new computer navigation system designed to help surgeons achieve better soft tissue balance during total knee replacement surgery. The goal was to see if using this technology during the operation could improve patient outcomes and recovery. Forty patients who…
Matched conditions: MUSCULOSKELETAL DISEASES
Phase: NA • Sponsor: Medacta International SA • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Could a laser beam ease the pain of stroke recovery?
Symptom relief CompletedThis study tested whether high-intensity laser therapy could help reduce shoulder pain and improve movement in people recovering from a stroke. It involved 40 stroke survivors with shoulder pain, comparing laser therapy plus exercise to exercise alone. The goal was to see if the …
Matched conditions: MUSCULOSKELETAL DISEASES
Phase: NA • Sponsor: Afyonkarahisar Health Sciences University • Aim: Symptom relief
Last updated Mar 18, 2026 14:42 UTC
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Decade-Long knee study seeks clues to prevent arthritis after ACL repair
Knowledge-focused CompletedThis study followed 225 people for 10 years after ACL knee surgery. Researchers measured knee joint space and pain levels to understand what factors lead to osteoarthritis. The goal is to identify risks like smoking, weight, or specific injury details to help future patients.
Matched conditions: MUSCULOSKELETAL DISEASES
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Mind, body, and spirit: how beliefs shape chronic pain experience
Knowledge-focused CompletedThis study aimed to understand the connections between what people with chronic pain believe about their pain, their spiritual well-being, and their attitudes toward complementary and alternative medicine (like acupuncture or herbal remedies). Researchers surveyed 116 adults with…
Matched conditions: MUSCULOSKELETAL DISEASES
Sponsor: Gulseren Demir Karakilic • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Could a physio see you in the ER? study tests new way to ease doctor shortage
Knowledge-focused CompletedThis study tested a new way to handle common muscle and joint pain in the emergency room. Researchers wanted to see if specially trained physiotherapists could safely assess, diagnose, and discharge patients as well as doctors could. Over 100 patients with non-urgent back, neck, …
Matched conditions: MUSCULOSKELETAL DISEASES
Phase: NA • Sponsor: Bern University of Applied Sciences • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Hidden pain: study probes arthritis in nursing homes
Knowledge-focused CompletedThis study aimed to find out how common joint pain and arthritis are among people living in nursing homes, including those with dementia. Researchers examined 100 residents to count painful or swollen joints and check their mobility. The goal was to gather better information to h…
Matched conditions: MUSCULOSKELETAL DISEASES
Sponsor: Maastricht University Medical Center • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Diet showdown: can a keto diet help aging muscles without harming bones?
Knowledge-focused CompletedThis small pilot study aimed to gather initial information on how two different diets affect bone health and muscle function in older adults. Researchers compared a very low-carb ketogenic diet to a Mediterranean diet over six weeks in 12 participants. The goal was to collect ear…
Matched conditions: MUSCULOSKELETAL DISEASES
Phase: NA • Sponsor: University of Florida • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC