New pill combo targets tough cancers in early trial

NCT ID NCT05538130

Recruiting now Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

Summary

This early-stage study is testing the safety and initial effects of a new oral medicine, PF-07799544, when taken with another drug, PF-07799933. It is for adults with advanced solid tumors, like melanoma or lung cancer, that have a specific genetic change called a BRAF V600 mutation. The main goal is to find a safe dose and see if the treatment helps control the cancer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

ANIMI - Unidade de Tratamento Oncologico
RECRUITING

Lages, Santa Catarina, 88501001, Brazil
Brigham and Women's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States
Brigitte Harris Cancer Pavilion
RECRUITING

Detroit, Michigan, 48202, United States
Brooklyn Radiation Oncology, PC
NOT_YET_RECRUITING

Richmond Hill, New York, 11418, United States
CUIMC Research Pharmacy
RECRUITING

New York, New York, 10032, United States
Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus
RECRUITING

Québec, Quebec, G1J 1Z4, Canada
Centro de Oncologia - CEON+ - Unidade São Caetano do Sul
RECRUITING

São Caetano do Sul, São Paulo, 09541-270, Brazil
Cleveland Clinic Taussig Cancer Center
RECRUITING

Cleveland, Ohio, 44195, United States
Cleveland Clinic Taussig Cancer Center Investigational Pharmacy
RECRUITING

Cleveland, Ohio, 44106, United States
Clinical Research Alliance
NOT_YET_RECRUITING

Westbury, New York, 11590, United States
Columbia University Irving Medical Center
RECRUITING

New York, New York, 10032, United States
Columbia University Medical Center - Neurological Institute of New York
RECRUITING

New York, New York, 10032, United States
Cross Cancer Institute
RECRUITING

Edmonton, Alberta, T6G 1Z2, Canada
Dana Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States
Dana-Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States
Fred Hutchinson Cancer Center
RECRUITING

Seattle, Washington, 98109, United States
Hadassah Medical Center
NOT_YET_RECRUITING

Jerusalem, Jerusalem, 9112001, Israel
HealthPartners Cancer Center at regions Hospital
NOT_YET_RECRUITING

Saint Paul, Minnesota, 55101, United States
HealthPartners Frauenshuh Cancer Center
NOT_YET_RECRUITING

Saint Louis Park, Minnesota, 55426, United States
Henry Ford Hospital
RECRUITING

Detroit, Michigan, 48202, United States
Highlands Oncology Group, PA
RECRUITING

Fayetteville, Arkansas, 72703, United States
Highlands Oncology Group, PA
RECRUITING

Rogers, Arkansas, 72758, United States
Highlands Oncology Group, PA
RECRUITING

Springdale, Arkansas, 72762, United States
IBCC - Núcleo de Pesquisa e Ensino
RECRUITING

São Paulo, 04014-002, Brazil
Jewish General Hospital
RECRUITING

Montreal, Quebec, H3T 1E2, Canada
Keck Hospital of USC
NOT_YET_RECRUITING

Los Angeles, California, 90033, United States
Keck Medical Center of USC Pasadena
NOT_YET_RECRUITING

Pasadena, California, 91105, United States
Laura & Isaac Perlmutter Cancer Center - NYU ACC
RECRUITING

New York, New York, 10016, United States
Laura & Isaac Perlmutter Cancer Center at NYU Langone Health
RECRUITING

New York, New York, 10016, United States
Los Angeles General Medical Center
NOT_YET_RECRUITING

Los Angeles, California, 90033, United States
MSK Basking Ridge.
RECRUITING

Basking Ridge, New Jersey, 07920, United States
MSK Bergen.
RECRUITING

Montvale, New Jersey, 07645, United States
MSK Commack.
RECRUITING

Commack, New York, 11725, United States
MSK Monmouth.
RECRUITING

Middletown, New Jersey, 07748, United States
MSK Nassau.
RECRUITING

Uniondale, New York, 11553, United States
MSK Westchester.
RECRUITING

Harrison, New York, 10604, United States
McGill University Health Centre
RECRUITING

Montreal, Quebec, H4A 3J1, Canada
Memorial Sloan Kettering Cancer Center - Main Campus
RECRUITING

New York, New York, 10065, United States
Memorial Sloan Kettering Cancer Center 53rd street.
RECRUITING

New York, New York, 10022, United States
Methodist Hospital Inpatient Pharmacy
NOT_YET_RECRUITING

Saint Louis Park, Minnesota, 55426, United States
Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States
Moffitt Cancer Center, Richard M. Shulze Family Foundation Outpatient Center
RECRUITING

Tampa, Florida, 33612, United States
Moffitt McKinley Hospital
RECRUITING

Tampa, Florida, 33612, United States
NYU Langone Faculty Group Practice
RECRUITING

New York, New York, 10016, United States
NYU Langone Medical Center (Tisch Hospital)
RECRUITING

New York, New York, 10016, United States
Optum Medical Care, PC
NOT_YET_RECRUITING

Brewster, New York, 10509, United States
Peter MacCallum Cancer Centre
RECRUITING

Melbourne, Victoria, 3000, Australia
Princess Margaret Cancer Centre
RECRUITING

Toronto, Ontario, M5G 2M9, Canada
Providence Cancer Institute Franz Clinic
RECRUITING

Portland, Oregon, 97213, United States
Providence Portland Medical Center
RECRUITING

Portland, Oregon, 97213, United States
Rabin Medical Center
RECRUITING

Petah Tikva, Central District, 4941492, Israel
Regions Hospital Pharmacy
NOT_YET_RECRUITING

Saint Paul, Minnesota, 55101, United States
Royal Melbourne Hospital
RECRUITING

Parkville, Victoria, 3052, Australia
SCRI Oncology Partners
RECRUITING

Nashville, Tennessee, 37203, United States
Sarah Cannon Research Institute- Pharmacy
RECRUITING

Nashville, Tennessee, 37203, United States
Sheba Medical Center
RECRUITING

Ramat Gan, Central District, 5265601, Israel
Soroka Medical Center
RECRUITING

Beersheba, Southern District, 8410101, Israel
Sourasky Medical Center
RECRUITING

Tel Aviv, TELL ABĪB, 6423906, Israel
Sunnybrook Research Institute
RECRUITING

Toronto, Ontario, M4N 3M5, Canada
The Alfred Hospital
RECRUITING

Melbourne, Victoria, 3004, Australia
The Angeles Clinic and Research Institue, A Cedars-Sinai Affiliate (Emergency Back-up only)
RECRUITING

Santa Monica, California, 90404, United States
The Angeles Clinic and Research Institute- A Cedars-Sinai Affiliate
RECRUITING

Los Angeles, California, 90025, United States
The Kirklin Clinic of UAB Hospital
NOT_YET_RECRUITING

Birmingham, Alabama, 35233, United States
The Ottawa Hospital - General Campus
RECRUITING

Ottawa, Ontario, K1H 8L6, Canada
The University of Alabama at Birmingham
NOT_YET_RECRUITING

Birmingham, Alabama, 35249, United States
UCSF Helen Diller Family Comprehensive Cancer Center
NOT_YET_RECRUITING

San Francisco, California, 94143, United States
UCSF Medical Center, Investigational Pharmacy
NOT_YET_RECRUITING

San Francisco, California, 94158, United States
UPMC Hillman Cancer Center
NOT_YET_RECRUITING

Pittsburgh, Pennsylvania, 15232, United States
USC/Norris Comprehensive Cancer Center
NOT_YET_RECRUITING

Los Angeles, California, 90033, United States
University of Alabama at Birmingham - Phase I Clinical Trials Unit
NOT_YET_RECRUITING

Birmingham, Alabama, 35249, United States
University of Texas MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
University of Washington Medical Center
RECRUITING

Seattle, Washington, 98195, United States
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center
NOT_YET_RECRUITING

Madison, Wisconsin, 53718, United States
University of Wisconsin Carbone Cancer Center - University Hospital
NOT_YET_RECRUITING

Madison, Wisconsin, 53792, United States
Zhejiang Cancer Hospital
NOT_YET_RECRUITING

Hangzhou, Zhejiang, 310022, China

Conditions

Explore the condition pages connected to this study.

ADVANCED OR METASTATIC SOLID TUMORS BRAIN NEOPLASMS COLORECTAL CANCER DIFFERENTIATED THYROID CANCER GLIOMA HGG HIGH GRADE GLIOMA LGG LOW-GRADE GLIOMA MALIGNANT NEOPLASMS MELANOMA NON SMALL CELL LUNG CANCER NSCLC NON-SMALL CELL LUNG CANCER THYROID CANCER