New injection could unpinch nerves in diabetic legs
NCT ID NCT07625020
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a single ultrasound-guided injection of medicine around compressed leg nerves can relieve numbness, pain, and weakness in people with diabetes. 266 participants will be randomly assigned to get the real injection or a sham (fake) injection, and neither they nor the researchers will know who got which. The main goal is to see if nerve function improves one month later.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- mecobalamin and normal saline injection
- What this could lead to
- If it works, this could offer a new, minimally invasive way to relieve nerve compression symptoms in diabetic patients, potentially improving quality of life.
- What could go wrong
- This is a single-session procedure with a modest primary endpoint (1-point improvement on a scale). The sham control may show similar benefits, and long-term effects are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The First Affiliated Hospital of Chongqing Medical University
RECRUITINGChongqing, Chongqing Municipality, 400016, China
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