Sound waves aimed at the brain could tame tough seizures

NCT ID NCT04999046

Completed Symptom relief Sponsor: NaviFUS Corporation Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tested a device called NaviFUS that uses focused ultrasound to stimulate the brain in 12 adults with drug-resistant epilepsy. The goal was to see if it is safe and can reduce seizure frequency. Participants kept seizure diaries and reported any side effects over two months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: focused ultrasound (NaviFUS system)
What this could lead to: If it works, this could point toward a non-invasive treatment option for people with epilepsy that doesn't respond to medication.
What could go wrong: This is a very small pilot study with only 12 participants, so results may not apply to everyone. The treatment is still experimental and its long-term safety and effectiveness are not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Drug Resistant Epilepsy epilepsy visual epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DRUG-RESISTANT EPILEPSY EPILEPSY SEIZURE SEIZURE DISORDER

Contacts and locations

Locations

Taipei Veterans General Hospital

Taipei, 11217, Taiwan

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