New combo surgery for obesity and reflux tested – but study stopped early
NCT ID NCT04626232
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aimed to compare a standard sleeve gastrectomy (removing part of the stomach) with a modified version called N-Sleeve, which adds a wrap around the top of the stomach to prevent acid reflux. The trial was designed for people with severe obesity and GERD, but only 2 patients enrolled before the study was terminated. Because it stopped so early, we cannot draw any meaningful conclusions about which surgery might be better.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- surgical procedure (N-Sleeve: sleeve gastrectomy with Nissen fundoplication)
- What this could lead to
- If successful, the N-Sleeve technique could reduce acid reflux after weight-loss surgery, potentially improving quality of life for people with severe obesity and GERD.
- What could go wrong
- The trial was terminated early with only 2 participants, so no reliable conclusions can be drawn. The added procedure may also carry extra surgical risks.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU Montpellier
Montpellier, 34295, France
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