Can immune cells heal the heart and brain after attack?

NCT ID NCT04321512

NEW Recruiting now Knowledge-focused Sponsor: UConn Health Source: ClinicalTrials.gov ↗

First seen Aug 17, 2026 · Last updated Aug 17, 2026

Summary

This study looks at how certain white blood cells, called monocytes, react to injury from a heart attack or ischemic stroke. Researchers want to learn how these cells sense danger signals and produce substances that might help heart muscle and brain tissue heal. The study involves adults who have had a heart attack, stroke, or stable coronary artery disease, and it tracks their health over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could uncover how monocytes promote healing after heart attack or stroke, potentially pointing toward new therapies that boost recovery.
What could go wrong: This is an observational study, so it won't directly test a treatment. Findings may not translate into immediate clinical benefits, and the role of monocytes in healing is complex and not fully understood.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder ischemic disease ischemic stroke myocardial infarction ST-elevation myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ISCHEMIA MYOCARDIAL INFARCTION STROKE, ISCHEMIC

Contacts and locations

Locations

University of Connecticut Health Center
RECRUITING

Farmington, Connecticut, 06030, United States

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