New knee implant aims to ease arthritis pain without major surgery

NCT ID NCT06843980

Recruiting now Symptom relief Sponsor: Moximed Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 15, 2026 · Updated 3 times

Summary

This study tests a device called the MISHA Knee System, a small implant placed under the skin near the knee to absorb shock and reduce pain from medial knee osteoarthritis. Researchers will compare it to non-surgical treatments like physical therapy and medication in 100 adults who haven't found relief. The goal is to see if the implant improves pain and knee function after 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: MISHA Knee System (a knee implant that absorbs shock to reduce pressure on the inner knee)
What this could lead to: If it works, this could offer a new option for people with knee osteoarthritis who haven't found relief from non-surgical treatments, potentially reducing pain and improving function.
What could go wrong: This is an early head-to-head study with only 100 participants, so results may not apply to everyone. The implant requires surgery, which carries risks like infection or device issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS, KNEE

Contacts and locations

Locations

Genesis Orthopedics & Sports Medicine
RECRUITING

Oak Brook, Illinois, 60523, United States
NYU Langone Health
ACTIVE_NOT_RECRUITING

New York, New York, 10016, United States
Ohio State Jameson Crane Sports Medicine Institute
RECRUITING

Columbus, Ohio, 43202, United States
Rush University Medical Center
RECRUITING

Chicago, Illinois, 60612, United States
Scripps Clinic Jefferson
RECRUITING

Oceanside, California, 92054, United States
Sutter Health
ACTIVE_NOT_RECRUITING

Sacramento, California, 95816, United States
UC Davis Department of Orthopaedic Surgery
TERMINATED

Davis, California, 95816, United States
UT Health San Antonio
RECRUITING

San Antonio, Texas, 78249, United States
University of Nebraska Medical Center
RECRUITING

Omaha, Nebraska, 68198, United States

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