Belly band or pill? study tests best way to treat dizzy spells in nerve disease

NCT ID NCT04620382

Completed Knowledge-focused Sponsor: Vanderbilt University Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This study looked at two common treatments for low blood pressure upon standing in people with autonomic failure: the drug midodrine and an abdominal compression belt. Researchers measured how each affects heart health markers like pulse wave velocity. The trial involved 31 adults aged 40-80 with conditions like Parkinson's disease or multiple system atrophy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Midodrine
What this could lead to: If successful, this could help doctors choose the best treatment for low blood pressure in autonomic failure patients to reduce heart risks.
What could go wrong: This is a very early, small study with only 31 participants, so results may not apply to everyone. It looks at short-term markers, not long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

multiple system atrophy Parkinson disease primary orthostatic hypotension pure autonomic failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTONOMIC FAILURE MULTIPLE SYSTEM ATROPHY NEUROGENIC ORTHOSTATIC HYPOTENSION PARKINSON DISEASE PURE AUTONOMIC FAILURE

Contacts and locations

Locations

Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States

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