Tiny brain probe aims to spy on seizures

NCT ID NCT05335187

Recruiting now Knowledge-focused Sponsor: Pierre Mégevand Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a special electrode that can record the activity of individual brain cells during epileptic seizures. Thirty adults with drug-resistant epilepsy who already need brain monitoring for surgery will have these electrodes implanted for a few weeks. The main goal is to see if the device is safe and can capture clear signals from single neurons.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: micro-macro electrode implantation
What this could lead to: If successful, this could help researchers better understand how seizures start and spread in the brain, potentially guiding future treatments.
What could go wrong: This is a small, early-stage safety study with only 30 participants. The device may cause side effects or fail to record enough neurons, and the findings may not lead to direct patient benefits.

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Conditions

The condition(s) this trial relates to.

Drug Resistant Epilepsy epilepsy focal epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EPILEPSY

Contacts and locations

Locations

Hôpitaux Universitaires de Genève
RECRUITING

Geneva, CH, 1205, Switzerland
Inselspital Bern
RECRUITING

Bern, Canton of Bern, 3010, Switzerland

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