Can a sugar solution stop blood pressure drops during dialysis?
NCT ID NCT04428372
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether giving mannitol during hemodialysis can prevent blood pressure drops and reduce symptoms like dizziness. Thirty-one adults prone to low blood pressure during dialysis received either mannitol or a saline placebo. The goal was to see if mannitol improves comfort and stability during treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Mannitol
What this could lead to
If it works, mannitol could become a simple option to help dialysis patients avoid low blood pressure and feel better during treatment.
What could go wrong
This is a small, early-phase study with only 31 participants, so results may not apply to everyone. Mannitol may not work better than saline, and side effects are possible.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Brigham and Women's
Boston, Massachusetts, 02115, United States