Dialysis patients may straighten up with In-Chair exercise
NCT ID NCT07720401
First seen Jul 22, 2026 · Last updated Sep 02, 2026 · Updated 5 times
Summary
This trial investigates whether a 12-week supervised exercise program, done during regular hemodialysis sessions, can improve postural problems like hunched back and forward head posture in adults with end-stage renal disease. Participants will be randomly assigned to either the exercise program plus usual care or usual care alone. The study measures changes in spine curvature, balance, mobility, and physical function.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a supervised exercise program performed during dialysis sessions
- What this could lead to
- If effective, this exercise program could become a standard part of dialysis care to improve posture, balance, and mobility.
- What could go wrong
- This is a small, early-stage trial. The exercises may not produce meaningful improvements, and some participants may find them difficult or uncomfortable.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 98 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2026
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18-80 years * Diagnosed with ESRD and receiving stable maintenance hemodialysis for at least 3 months at the participating center, with a dialysis frequency of three sessions per week * Confirmed presence of at least one postural abnormality (hyperkyphosis ≥53° in women or ≥55° in men, or CVA \<53°) assessed at screening * Written informed consent obtained, indicating decision-making capacity and willingness to participate * Medical clearance from attending nephrologist to participate in supervised exercise during dialysis * Ability to sit upright in a dialysis chair and perform seated or supported standing exercises * Ability to communicate in Persian and understand study instructions Exclusion Criteria: * Unstable cardiovascular status, including recent (within 3 months) myocardial infarction, unstable angina, decompensated congestive heart failure (NYHA Class III-IV), or uncontrolled arrhythmia * Active infection, acute febrile illness, or acute medical condition requiring hospitalization * Hemodynamic instability defined as systolic blood pressure \<90 mmHg or \>200 mmHg, or severe orthostatic hypotension, at screening or prior to exercise sessions * Uncontrolled diabetes mellitus with labile glycemic control (blood glucose \<4 mmol/L or \>22 mmol/L at dialysis session start) * Severe musculoskeletal pain at rest or with minimal activity (Numeric Pain Rating Scale ≥7/10) that would preclude exercise participation * Inability to perform seated exercises, walk independently, or maintain upright posture; severe neurological disability * Recent fracture (within 6 months) of vertebral column, pelvis, or lower extremities * Severe peripheral neuropathy or vascular disease (ABI \<0.6) precluding lower limb exercise * Dyspnea at rest or with activities of daily living corresponding to NYHA Class IV * Participation in a structured exercise program targeting postural correction, resistance, or balance training ≥3 times per week in the preceding 3 months * Severe cognitive impairment (MMSE \<18) preventing informed consent or adherence to exercise instruction * Pregnancy or planned pregnancy during the study period * Life expectancy \<6 months as determined by the attending nephrologist * Scheduled kidney transplantation within the study period
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Pardis specialized wellness institute
RECRUITINGIsfahan, Iran
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