Can a statin and diet tweak protect hearts of epilepsy patients on High-Fat diets?
NCT ID NCT06369571
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a statin drug (atorvastatin) and swapping some saturated fats for healthier ones can safely lower cholesterol in adults with epilepsy who have been on a modified Atkins diet for at least a year. The diet helps control seizures but can raise cholesterol. The trial will track diet adherence, cholesterol changes, and seizure frequency over 12 weeks in 22 participants. The goal is to find a way to manage heart risks without losing seizure control.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Atorvastatin (Lipitor) and dietary fat modification
What this could lead to
If successful, this could offer a safe way to manage cholesterol in adults with epilepsy who need a high-fat diet for seizure control, reducing heart disease risk.
What could go wrong
This is a small, early-phase study with only 22 participants, so results may not apply widely. Statins can cause muscle pain or other side effects, and diet changes might affect seizure control.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Johns Hopkins Hospital
Baltimore, Maryland, 21287, United States