Massive study tracks hidden liver dangers of common drugs and herbal remedies

NCT ID NCT00345930

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to collect detailed information from 4,000 people who have experienced liver injury possibly caused by prescription drugs or complementary and alternative medicines. Researchers will track participants over time, using blood tests and liver scans to better understand how these injuries happen and how they progress. The goal is to build a database that helps doctors recognize and manage such injuries in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors better identify which drugs or supplements cause liver injury and how to prevent it.

What could go wrong

This is an observational study, not a treatment trial, so it won't directly help participants. It may take years to gather enough data for meaningful conclusions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

drug-induced liver injury liver disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Indiana University

    RECRUITING

    Indianapolis, Indiana, 46202-5111, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • NIH Clinical Site

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Thomas Jefferson

    RECRUITING

    Philadelphia, Pennsylvania, 19141, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Univeristy of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27599-7600, United States

    Contact Email: •••••@•••••

    Contact

    Contact

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109-0362, United States

    Contact Email: •••••@•••••

    Contact

  • University of Southern California

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••