Massive study tracks hidden liver dangers of common drugs and herbal remedies

NCT ID NCT00345930

Recruiting now Knowledge-focused Sponsor: Duke University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to collect detailed information from 4,000 people who have experienced liver injury possibly caused by prescription drugs or complementary and alternative medicines. Researchers will track participants over time, using blood tests and liver scans to better understand how these injuries happen and how they progress. The goal is to build a database that helps doctors recognize and manage such injuries in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors better identify which drugs or supplements cause liver injury and how to prevent it.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly help participants. It may take years to gather enough data for meaningful conclusions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

drug-induced liver injury liver disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LIVER DISEASES

Contacts and locations

Locations

Indiana University
RECRUITING

Indianapolis, Indiana, 46202-5111, United States
NIH Clinical Site
RECRUITING

Bethesda, Maryland, 20892, United States
Thomas Jefferson
RECRUITING

Philadelphia, Pennsylvania, 19141, United States
Univeristy of North Carolina at Chapel Hill
RECRUITING

Chapel Hill, North Carolina, 27599-7600, United States
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109-0362, United States
University of Southern California
RECRUITING

Los Angeles, California, 90033, United States

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