Intensive weight loss program aims to transform care for severe obesity
NCT ID NCT06321458
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares an intensive weight loss program—including meal replacements, behavioral support, and weight-loss medication—against standard care for adults with severe and complex obesity. The goal is to see if the intensive approach leads to better health outcomes and is cost-effective. 600 participants aged 18-60 with a BMI over 35 (or slightly lower for certain ethnic groups) and related health issues like heart disease or diabetes are being recruited.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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East of England RRDN
NOT_YET_RECRUITINGIpswich, United Kingdom
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Frederiksberg kommune: Social-, Sundheds- og Arbejdsmarkedsområdet
RECRUITINGFrederiksberg, 2000, Denmark
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Gladsaxe kommune: Social- og Sundhedsforvaltningen, Sundhed og Rehabilitering
RECRUITINGSøborg, 2860, Denmark
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Hvidovre kommune: Center for Sundhed og Ældre, Hvidovre Sundhedscenter, Sundhed og Forebyggelse
RECRUITINGHvidovre, 2650, Denmark
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Powys Teaching Health Board
NOT_YET_RECRUITINGPowys, United Kingdom
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Royal Wolverhampton NHS Trust
NOT_YET_RECRUITINGWolverhampton, United Kingdom
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South Central RRDN
NOT_YET_RECRUITINGSouthampton, United Kingdom
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South West Peninsula RRDN
NOT_YET_RECRUITINGPlymouth, United Kingdom
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The Department of Medicine and the Gastro Unit, Copenhagen University Hospital - Amager and Hvidovre
RECRUITINGHvidovre, 2650, Denmark
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The Parker Institute, Copenhagen University Hospital - Bispebjerg and Frederiksberg
RECRUITINGFrederiksberg, 2000, Denmark
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Torbay and South Devon NHS Trust
NOT_YET_RECRUITINGTorquay, United Kingdom
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University Hospitals Birmingham NHS Foundation Trust
NOT_YET_RECRUITINGBirmingham, United Kingdom
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University Hospitals of Derby and Burton NHS Foundation Trust
RECRUITINGDerby, United Kingdom
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Yorkshire and Humber RRDN (Leeds, Sheffield and Hull)
RECRUITINGLeeds, United Kingdom
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