New pacemaker technique aims to boost heart failure treatment

NCT ID NCT05769036

Recruiting now Disease control Sponsor: Tomsk National Research Medical Center of the Russian Academy of Sciences Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a newer pacing method called left bundle branch pacing (LBBP) works better than the standard biventricular pacing for people with chronic heart failure and reduced pumping ability. About 60 adults with heart failure and a specific electrical delay in the heart will receive a special pacemaker-defibrillator using one of the two techniques. The goal is to see if LBBP can improve heart function, reduce hospitalizations, and lower the risk of death.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cardiac resynchronization therapy device (pacemaker/defibrillator) with left bundle branch pacing or biventricular pacing
What this could lead to: If successful, this could offer a more effective pacing method for heart failure patients, potentially reducing hospitalizations and improving heart function compared to current standard therapy.
What could go wrong: This is a small, early-stage study with only 60 participants, so results may not apply to all patients. The new pacing method may not prove superior or could have unforeseen complications.

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Conditions

The condition(s) this trial relates to.

cardiomyopathy dilated cardiomyopathy heart failure left ventricular failure non-familial dilated cardiomyopathy progressive familial heart block, type 1A systolic heart failure Ventricular Dysfunction, Left Ventricular Remodeling

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE ISCHEMIC CARDIOMYOPATHY LEFT BUNDLE-BRANCH BLOCK LEFT VENTRICLE REMODELING LEFT VENTRICULAR DYSFUNCTION LEFT VENTRICULAR DYSSYNCHRONY NON-ISCHEMIC DILATED CARDIOMYOPATHY

Contacts and locations

Locations

Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
RECRUITING

Tomsk, Russia

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