New radiation method aims to shrink large tumors better

NCT ID NCT07594431

Not yet recruiting Disease control Sponsor: Stanford University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial compares a new type of radiation called LATTICE radiotherapy with standard palliative radiation for people who have large metastatic tumors (over 2.5 cm). The LATTICE method delivers a very high dose to the center of the tumor while keeping lower doses to the surrounding area. The study will enroll 80 patients and measure how much the tumor shrinks 90 days after treatment. The goal is to see if this approach works better than the standard treatment for controlling tumor growth.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: LATTICE radiotherapy (a type of radiation that delivers a high dose to the center of the tumor while keeping lower doses to surrounding tissue)
What this could lead to: If it works, this could offer a more effective way to shrink large metastatic tumors, potentially improving symptom control and quality of life.
What could go wrong: This is a small, early-phase trial with only 80 participants, so results may not apply to everyone. The higher radiation dose could also increase side effects like pain or damage to nearby organs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

metastatic malignant neoplasm metastatic neoplasm Neoplasm Metastasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METASTASES METASTATIC CANCER

Contacts and locations

Locations

Stanford University

Palo Alto, California, 94304, United States

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