Could a simple salt solution save lives in septic shock?

NCT ID NCT06634069

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two fluids—sodium lactate and a concentrated saline solution—in 40 adults with septic shock. The goal is to see which one better supports blood flow and acid balance. Participants will receive either fluid in a double-blind setup, and researchers will measure heart function and blood chemistry.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SEPTIC SHOCK are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Hospital Pilsen

    RECRUITING

    Pilsen, Czech Republic, 30100, Czechia

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Sodium lactate solution (0.5M) and 3% saline solution

What this could lead to

If this works, it could point toward a better fluid treatment for septic shock, potentially improving blood flow and acid balance in critically ill patients.

What could go wrong

This is a small, early-phase pilot study with only 40 participants, so results may not apply broadly. The treatments are given in a hospital setting and may not work better than standard care.

Conditions

The condition(s) this trial relates to.

intracranial hypertension toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.