Could a simple salt solution save lives in septic shock?

NCT ID NCT06634069

Recruiting now Disease control Sponsor: University Hospital Pilsen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two fluids—sodium lactate and a concentrated saline solution—in 40 adults with septic shock. The goal is to see which one better supports blood flow and acid balance. Participants will receive either fluid in a double-blind setup, and researchers will measure heart function and blood chemistry.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Sodium lactate solution (0.5M) and 3% saline solution
What this could lead to: If this works, it could point toward a better fluid treatment for septic shock, potentially improving blood flow and acid balance in critically ill patients.
What could go wrong: This is a small, early-phase pilot study with only 40 participants, so results may not apply broadly. The treatments are given in a hospital setting and may not work better than standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

intracranial hypertension toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTRACRANIAL HYPERTENSION SEPTIC SHOCK

Contacts and locations

Locations

University Hospital Pilsen
RECRUITING

Pilsen, Czech Republic, 30100, Czechia

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