New study aims to find best pain relief after knee replacement

NCT ID NCT07267650

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at two different methods to control pain after total knee replacement. One method combines two nerve blocks given by an anesthesiologist, while the other uses a nerve block plus a local painkiller injection by the surgeon. Researchers will review the medical records of 100 patients to see which approach leads to less pain during movement 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nerve block (iPACK block) and local anesthetic infiltration

What this could lead to

If successful, this could show that a specific nerve block combination provides better pain control after knee replacement, potentially improving recovery and reducing opioid use.

What could go wrong

This is a small, retrospective study at a single hospital, so results may not apply to all patients. It only looks at past records, not a controlled experiment, so other factors could influence the outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

agnosia osteoarthritis osteoarthritis, knee Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Turgutlu State Hospital+

    Manisa, Manisa, 45000, Turkey (Türkiye)