Knee replacement pain study aims to cut chronic pain risk
NCT ID NCT03998813
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two ways to manage pain after total knee replacement: a continuous nerve block using a catheter near the femoral triangle versus tissue infiltration with a local anesthetic. The goal is to see which method better prevents long-term chronic pain and improves knee function. About 287 adults scheduled for knee replacement will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ropivacaine
What this could lead to
If successful, this could point to a better way to manage pain after knee replacement, reducing the chance of long-term chronic pain and improving recovery.
What could go wrong
This is a single-center study, and results may not apply to all patients. The two techniques may show little difference, or one may have unexpected side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Centre Hospitalier Départemental Vendée
La Roche-sur-Yon, 85925, France
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Centre Hospitalier de Béthune Beuvry
Béthune, France
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Clinique Victor PAUCHET
Amiens, France
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Hôpital Privé Sévigné
Rennes, France
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Hôpital des Diaconesses Croix Saint Simon
Paris, France