Knee replacement pain study aims to cut chronic pain risk

NCT ID NCT03998813

Completed Symptom relief Sponsor: Centre Hospitalier Departemental Vendee Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two ways to manage pain after total knee replacement: a continuous nerve block using a catheter near the femoral triangle versus tissue infiltration with a local anesthetic. The goal is to see which method better prevents long-term chronic pain and improves knee function. About 287 adults scheduled for knee replacement will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ropivacaine
What this could lead to: If successful, this could point to a better way to manage pain after knee replacement, reducing the chance of long-term chronic pain and improving recovery.
What could go wrong: This is a single-center study, and results may not apply to all patients. The two techniques may show little difference, or one may have unexpected side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KNEE PAIN CHRONIC

Contacts and locations

Locations

Centre Hospitalier Départemental Vendée

La Roche-sur-Yon, 85925, France
Centre Hospitalier de Béthune Beuvry

Béthune, France
Clinique Victor PAUCHET

Amiens, France
Hôpital Privé Sévigné

Rennes, France
Hôpital des Diaconesses Croix Saint Simon

Paris, France

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