Ozone injection study: does concentration matter for knee pain?

NCT ID NCT07662512

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a higher concentration of ozone injected into the knee works better than a lower concentration for treating osteoarthritis. 159 patients received one of two ozone strengths and were followed for 3 months. Researchers measured pain, stiffness, and daily function to see if concentration made a difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ozone injection
What this could lead to
If successful, this could show that a specific ozone concentration provides better pain relief and function for people with knee osteoarthritis.
What could go wrong
This is a small, completed trial with only 3 months of follow-up. Results may not apply to all patients, and longer-term benefits or risks are unknown.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sakarya University

    Adapazarı, Sakarya, 54010, Turkey (Türkiye)

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