Knee gel injection aims to ease arthritis pain without surgery

NCT ID NCT06611098

Completed Symptom relief Sponsor: Symatese Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This clinical trial tests a gel called ABIO3419, injected into the knee joint, to see if it safely reduces pain and improves function in people with knee osteoarthritis. The study compares ABIO3419 to another treatment and measures pain relief over three months. Participants are adults aged 35 to 85 with moderate knee osteoarthritis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ABIO3419 (viscosupplement gel)
What this could lead to: If it works, this could offer a safe, non-surgical option to reduce knee pain and improve mobility for people with osteoarthritis.
What could go wrong: This is an early-stage trial with 134 participants, so results may not apply to everyone. Possible side effects include temporary pain, swelling, or joint discomfort at the injection site.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KNEE OSTEOARTHRISTIS

Contacts and locations

Locations

IRIS CRO

Mtskheta, 3300, Georgia
IRIS CRO

Riga, 1002, Latvia

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