Knee gel injection aims to ease arthritis pain without surgery
NCT ID NCT06611098
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This clinical trial tests a gel called ABIO3419, injected into the knee joint, to see if it safely reduces pain and improves function in people with knee osteoarthritis. The study compares ABIO3419 to another treatment and measures pain relief over three months. Participants are adults aged 35 to 85 with moderate knee osteoarthritis.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ABIO3419 (viscosupplement gel)
What this could lead to
If it works, this could offer a safe, non-surgical option to reduce knee pain and improve mobility for people with osteoarthritis.
What could go wrong
This is an early-stage trial with 134 participants, so results may not apply to everyone. Possible side effects include temporary pain, swelling, or joint discomfort at the injection site.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Freedom Total Knee System Registry NCT06627699
- Ozone Injection for Knee Osteoarthritis – NCT07662512
- ACT-ON: Physical Therapy for Knee Osteoarthritis NCT07640529
- Wearable Exoskeleton for Knee OA Mobility - NCT07652437
- Prehab2Rehab: Prehabilitation for Knee Replaceme NCT07621666
- Blood-Flow Exercise & Pain Education for Knee OA NCT07590323
Contacts and locations
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Locations
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IRIS CRO
Mtskheta, 3300, Georgia
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IRIS CRO
Riga, 1002, Latvia